Feasibility of a Mitral Annuloplasty With the Capability for Peri- and Postoperative Adjustment

Autor: Jacob Brubert, Geoff D. Moggridge, Steven Tsui, Paul De Sciscio
Přispěvatelé: Apollo - University of Cambridge Repository
Rok vydání: 2020
Předmět:
Zdroj: Journal of Medical Devices. 14
ISSN: 1932-619X
1932-6181
DOI: 10.1115/1.4046669
Popis: Surgical repair with implantation of a mitral annuloplasty ring is the gold standard treatment for mitral regurgitation. However, outcomes are variable and recurrent mitral regurgitation is not uncommon. A REshapeable Mitral Annuloplasty DevIce (REMADI) is proposed, which consists of a fully encapsulated low melting temperature alloy. The alloy is solid and rigid at body temperature and provides traction force to shape the annulus. When heated using a noncontact method, the alloy melts and the REMADI becomes malleable. The REMADI is engaged with the mitral valve annulus using anchors which automatically deploy upon contact. A passive beating porcine heart model was used to demonstrate the feasibility of the REMADI device, which was deployed, engaged, and used to reduce the diameter of the mitral valve annulus.
Databáze: OpenAIRE