A single-center study on total mastectomy versus skin-sparing mastectomy in case of pure ductal carcinoma in situ of the breast
| Autor: | Simone Mathoulin-Pélissier, H. Charitansky, Aurélien Rousvoal, M. Fournier, S. Croce, Christine Tunon de Lara, Margaux l'Henaff, Florence Chassaigne, Houda Ben Rejeb, Gaëtan MacGrogan, Vincent Pinsolles, Véronique Brouste, E. Bussieres |
|---|---|
| Přispěvatelé: | Université de Bordeaux (UB) |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Mammaplasty [SDV]Life Sciences [q-bio] medicine.medical_treatment Breast Neoplasms 030230 surgery Single Center 03 medical and health sciences 0302 clinical medicine medicine Humans skin and connective tissue diseases Total Mastectomy Mastectomy Aged Retrospective Studies business.industry Standard treatment Retrospective cohort study General Medicine Middle Aged Ductal carcinoma Prognosis 3. Good health Survival Rate Carcinoma Intraductal Noninfiltrating Oncology 030220 oncology & carcinogenesis Population study Female Surgery France Radiology business Breast reconstruction Follow-Up Studies |
| Zdroj: | EJSO-European Journal of Surgical Oncology EJSO-European Journal of Surgical Oncology, WB Saunders, 2019, 45, pp.950-955. ⟨10.1016/j.ejso.2019.01.014⟩ |
| ISSN: | 0748-7983 |
| Popis: | Introduction Ductal carcinoma in situ (DCIS) accounts for 15% of all breast cancers and generally, the prognosis is good if treated optimally. The standard treatment includes breast conservative surgery along with adjuvant radiotherapy. Skin-sparing mastectomy (SSM) preserves the breast skin envelope but its oncological safety poses a few concerns. Moreover, no DCIS-specific studies have compared the local recurrence (LR) rate following total mastectomy (TM) or SSM. We evaluated the LR rate in DCIS patients who underwent either TM or SSM. Methods This is a retrospective study on women who underwent mastectomy with or without immediate breast reconstruction or secondary reconstruction for pure DCIS of the breast. All patients treated at Institut Bergonie by mastectomy for DCIS from January 1990 to December 2010 were included. LR and overall survival (OS) rates were estimated. Results The study population included 399 patients who were categorized into two groups, 207 in the TM group and 192 in the SSM group. At 10 years of follow-up, the LR rate was 0.97% in the TM group and 1.04% in the SSM group (p = NS). The OS of the entire population was 94.7% [95% CI; 91.6–96.7], 92.8% [95% CI, 87.9–95.8] for the TM group and 96.8% [95% CI, 91.6–98.8] for the SSM group. Conclusions In our study, the LR rate following mastectomy is low, regardless of the surgical technique used, with an excellent OS at 10 years. |
| Databáze: | OpenAIRE |
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