REBELOTE , a regulator of floral determinacy in Arabidopsis thaliana , interacts with both nucleolar and nucleoplasmic proteins
| Autor: | Ioan Negrutiu, Stève de Bossoreille, Christophe Trehin, Patrice Morel |
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| Přispěvatelé: | Reproduction et développement des plantes (RDP), École normale supérieure - Lyon (ENS Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Region Rhone-Alpes, École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Région Rhône-Alpes |
| Rok vydání: | 2018 |
| Předmět: |
OBERON
0301 basic medicine Arabidopsis thaliana Nucleolus [SDV]Life Sciences [q-bio] cells genetic processes Regulator environment and public health General Biochemistry Genetics and Molecular Biology 03 medical and health sciences nucléoplasme [SDV.BV]Life Sciences [q-bio]/Vegetal Biology nucleolus REBELOTE ENAP1 NOC nucleoplasm OBE1 VFP3 Research Articles nucléole Regulation of gene expression Nucleoplasm biology Chemistry hemic and immune systems détermination et réversion florale Meristem Ribosomal RNA biology.organism_classification Cell biology 030104 developmental biology lipids (amino acids peptides and proteins) Biogenesis Research Article |
| Zdroj: | FEBS Open Bio FEBS Open Bio, Wiley Open Access/Elsevier, 2018, 8 (10), pp.1636-1648. ⟨10.1002/2211-5463.12504⟩ FEBS Open Bio, 2018, pp.1-22. ⟨10.1002/2211⟩ FEBS Open Bio, Wiley Open Access/Elsevier, 2018, pp.1-22. ⟨10.1002/2211⟩ FEBS Open Bio 10 (8), 1636-1648. (2018) FEBS Open Bio, 2018, 8 (10), pp.1636-1648. ⟨10.1002/2211-5463.12504⟩ |
| ISSN: | 2211-5463 |
| Popis: | doi:10.1002/2211-5463.1250 Vérifier ultérieurement ce lien; International audience; The nucleoplasm and nucleolus are the two main territories of the nucleus. While specific functions are associated with each of these territories (such as mRNA synthesis in the nucleoplasm and ribosomal rRNA synthesis in thenucleolus), some proteins are known to be located in both. Here, we investigated the molecular function of REBELOTE (RBL), an Arabidopsis thalianaprotein previously characterized as a regulator of floral meristem termination. We show that RBL displays a dual localization, in the nucleolus and nucleoplasm. Moreover, we used direct and global approaches to demonstrate that RBL interacts with nucleic acid-binding proteins. It binds to the NOC proteins SWA2, AtNOC2 and AtNOC3 in both the nucleolus and nucleoplasm, and also to OBE1 and VFP3/ENAP1. Taking into account the identities of these RBL interactors, we hypothesise that RBL acts both in ribosomal biogenesis and in the regulation of gene expression. |
| Databáze: | OpenAIRE |
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