Long-term outcome of pregnancy complicating with severe aplastic anemia under supportive care

Autor: An-Shine Chao, Kuan-Ju Chen, Shen-Yuan Su, Shuenn-Dyh Chang, Horng Chang, Yao-Lung Chang, Hsiu-Huei Peng
Rok vydání: 2017
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 56, Iss 5, Pp 632-635 (2017)
ISSN: 1028-4559
DOI: 10.1016/j.tjog.2017.08.010
Popis: Objectives: Pregnancy associated with aplastic anemia (AA) is a rare and heterogeneous disorder. We aimed to identify and evaluate the maternal and pregnant outcomes of pregnancy-associated severe AA treated with supportive care. Materials and methods: A 25-year retrospective study was conducted at in a single center between 1990 and 2014 with pregnancy associated severe AA. In addition, relevant published cases of antenatally diagnosed pregnancy-associated severe AA after 1990 were identified by PubMed. The main goal was to determine the impact of various risk factors on maternal and fetal outcomes. Results: 15 women with 18 pregnancies were enrolled. With addition of the published reports in literature, a total of 36 cases were included for reference review. Univariate analysis showed that low platelet counts (
Databáze: OpenAIRE