Plasma hemopexin as a potential regulator of vascular responsiveness to angiotensin II
| Autor: | Winston W. Bakker, Floor Spaans, Theo Borghuis, Harry van Goor, Marijke M. Faas, Evert van Dijk, Joshua Buijnink, Loubna el Bakkali |
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| Přispěvatelé: | Pediatric surgery, ICaR - Ischemia and repair |
| Rok vydání: | 2012 |
| Předmět: |
angiotensin II receptor
Male medicine.medical_specialty Angiotensin receptor PROTEINS Regulator INHIBITION Plasma protein binding Biology SERUM chemistry.chemical_compound Downregulation and upregulation Hemopexin Pregnancy Internal medicine medicine Extracellular Animals Humans Angiotensin II Obstetrics and Gynecology vascular expansion POLYMORPHONUCLEAR LEUKOCYTES protease-like activity Cell biology body regions ATP Vasodilation PREECLAMPSIA Endocrinology chemistry Vasoconstriction hemopexin activity Female Adenosine triphosphate Protein Binding |
| Zdroj: | Bakker, W W, Spaans, F, el Bakkali, L, Borghuis, T, van Goor, H, van Dijk, E, Buijnink, J & Faas, M M 2013, ' Plasma Hemopexin as a Potential Regulator of Vascular Responsiveness to Angiotensin II ', Reproductive Sciences, vol. 20, no. 3, pp. 234-237 . https://doi.org/10.1177/1933719112446081 Reproductive Sciences, 20(3), 234-237. SAGE Publications Inc. |
| ISSN: | 1933-7205 1933-7191 |
| DOI: | 10.1177/1933719112446081 |
| Popis: | This brief review focuses on the functional activities of plasma hemopexin recently recognized by several authors. In particular, the protease-like activity of hemopexin in vitro is linked with downregulation of the vascular angiotensin II receptor in vivo, leading to vascular expansion. Also a potential mechanism of inhibition of hemopexin activity by extracellular adenosine triphosphate is considered. |
| Databáze: | OpenAIRE |
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