Fertility and pregnancy in inflammatory bowel disease
| Autor: | N. A. G. Mowat, Allan Templeton, T. S. Sinclair, Mark Hudson, G. M. M. Flett, P. W. Brunt |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent media_common.quotation_subject Population Fertility Disease Abortion Inflammatory bowel disease Crohn Disease Pregnancy Recurrence Risk Factors Internal medicine medicine Humans education media_common Retrospective Studies Crohn's disease education.field_of_study business.industry Pregnancy Outcome Obstetrics and Gynecology General Medicine Middle Aged medicine.disease Ulcerative colitis Surgery Abortion Spontaneous Colitis Ulcerative Female business |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 58(2) |
| ISSN: | 0020-7292 |
| Popis: | Objective: A retrospective study of women with inflammatory bowel disease, aged 16–45 years during the 20-year period 1967–1986, was carried out in North East Scotland. Method: Five-hundred and three women were identified: 15 patients had died from unrelated causes and 22 had emigrated, but 409 of the remaining 466 patients (88%) replied to the study questionnaire. Results: Women with ulcerative colitis and Crohn's disease had normal fertility when compared with the general population of north east Scotland. However, unresolved infertility problems were more frequent in women who had undergone surgery for inflammatory bowel disease compared with those who had not (12% vs. 5% for Crohn's disease; 25% vs. 7% for ulcerative colitis). Disease relapse rates did not increase in pregnancy. Conclusions: Overall, at conception women with active disease were as likely to have a normal full-term pregnancy as those in remission. However, spontaneous abortion occurred in five (36%) pregnancies of women who had undergone previous surgery for Crohn's disease and had evidence of recurrent disease. Three of these pregnancies were associated with active disease. |
| Databáze: | OpenAIRE |
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