Acute disseminated encephalomyelitis, a rare post-malaria neurological complication: Case report and review of the literature
| Autor: | Delfim Lopes, Ana Catarina Gonçalves, José Poças, Bianca Branco Ascenção, Joana Estalagem Sá, Mário Parreira, Maria Isabel Casella, Ana Paula Brito, Nuno Pinto Luis, Joana Carreira |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty 030231 tropical medicine Encephalopathy 03 medical and health sciences 0302 clinical medicine parasitic diseases Magnetic resonance imaging of the brain medicine Demyelinating disease Humans 030212 general & internal medicine Malaria Falciparum Cerebellar ataxia medicine.diagnostic_test biology business.industry Encephalomyelitis Acute Disseminated Public Health Environmental and Occupational Health Brain Magnetic resonance imaging Plasmodium falciparum Middle Aged medicine.disease biology.organism_classification Treatment Outcome Infectious Diseases Acute disseminated encephalomyelitis Steroids Nervous System Diseases medicine.symptom business Malaria |
| Zdroj: | Travel Medicine and Infectious Disease. 28:81-85 |
| ISSN: | 1477-8939 |
| DOI: | 10.1016/j.tmaid.2018.03.005 |
| Popis: | There are four neurological complications that can occur after malaria treatment at a time when the patient is aparasitaemic: delayed cerebellar ataxia, acute inflammatory demyelinating polyneuropathy, post-malaria neurological syndrome and acute disseminated encephalomyelitis (ADEM). The authors describe a case of a 54-year-old male who presented with encephalopathy and generalized seizures forty-three days after complete recovery from acute malaria by Plasmodium falciparum. Diagnosis of post-malaria ADEM was made based on the acute onset of the neurological symptoms, characteristic findings in magnetic resonance imaging of the brain and prompt response to steroid therapy. ADEM is an autoimmune demyelinating disease of the central nervous system that usually arises after an infection or vaccination. Its occurrence after malaria infection is relatively rare, and to the best of our knowledge there are only thirteen cases described in the literature. |
| Databáze: | OpenAIRE |
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