Automated Detection of Uninformative Frames in Pulmonary Optical Endomicroscopy

Autor: Paul McCool, David R. Wilson, Jody Westerfeld, Kevin Dhaliwal, Antonios Perperidis, Stephen McLaughlin, Yoann Altmann, Ahsan R. Akram
Rok vydání: 2017
Předmět:
Zdroj: Perperidis, A, Akram, A, Altmann, Y, McCool, P, Westerfield, J, Wilson, D, Dhaliwal, K & McLaughlin, S 2016, ' Automated detection of uninformative frames in pulmonary optical endomicroscopy (OEM) ', IEEE Transactions on Biomedical Engineering . https://doi.org/10.1109/TBME.2016.2538084
ISSN: 1558-2531
0018-9294
DOI: 10.1109/tbme.2016.2538084
Popis: Significance: Optical endomicroscopy (OEM) is a novel real-time imaging technology that provides endoscopic images at a microscopic level. The nature of OEM data, as acquired in clinical use, gives rise to the presence of uninformative frames (i.e., pure-noise and motion-artefacts). Uninformative frames can comprise a considerable proportion (up to > 25%) of a dataset, increasing the resources required for analyzing the data (both manually and automatically), as well as diluting the results of any automated quantification analysis. Objective: There is, therefore, a need to automatically detect and remove as many of these uninformative frames as possible while keeping frames with structural information intact. Methods: This paper employs Gray Level Cooccurrence Matrix texture measures and detection theory to identify and remove such frames. The detection of pure-noise and motion-artefacts frames is treated as two independent problems. Results: Pulmonary OEM frame sequences of the distal lung are employed for the development and assessment of the approach. The proposed approach identifies and removes uninformative frames with a sensitivity of 93% and a specificity of 92.6%. Conclusion: The detection algorithm is accurate and robust in pulmonary OEM frame sequences. Conditional to appropriate model refinement, the algorithms can become applicable in other organs.
Databáze: OpenAIRE