Double-blind, within-patient, randomized, clinical trial comparing fluorine-synthetic fiber socks with standard cotton socks in improving plantar psoriasis
| Autor: | Emiliano Schincaglia, Santo Raffaele Mercuri, Giovanni Lo Scocco, Simone Cazzaniga, Rosita Saraceno, Luigi Naldi, Sergio Chimenti |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty computer.internet_protocol Fluorine Compounds Dermatology Clothing law.invention Double blind Lesion Young Adult Double-Blind Method Randomized controlled trial law Psoriasis medicine Humans Cotton Fiber Foot Dermatoses Median score business.industry Textiles Percentage reduction Fluorine Middle Aged medicine.disease Surgery Treatment Outcome SOCKS Patient Satisfaction Female medicine.symptom business computer |
| Zdroj: | Journal of Dermatological Treatment. 25:26-29 |
| ISSN: | 1471-1753 0954-6634 |
| Popis: | Background: Rubbing the skin and trauma may influence the persistence of psoriasis over time. Objectives: To assess the impact of a new fabric made with a special fluorine-synthetic fiber in improving plantar psoriasis. Methods: A total of 20 patients with symmetrical lesions were randomized to receive on one side a sock made of fluorine-synthetic fiber and on the other side a sock made of cotton fabric for 4 weeks. The main outcome was the percentage reduction of lesional area. Results: In an intention-to-treat analysis, the median lesion reduction was 11.95% in fluorine-synthetic fiber arm and 11.89% in cotton arm (p = 0.776). Among secondary outcomes, patient global satisfaction showed a statistically significant median score of 32 toward fluorine-synthetic fiber arm (p = 0.011). Conclusion: In spite of our main negative results, it is important to continue investigating on the relation between textiles and skin disorders to improve patient well-being. |
| Databáze: | OpenAIRE |
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