Emulsion Droplet Crystallinity Attenuates Postprandial Plasma Triacylglycerol Responses in Healthy Men: A Randomized Double-Blind Crossover Acute Meal Study
| Autor: | Surangi H Thilakarathna, Samar Hamad, Melissa Brown, Amanda J. Wright, Amanda Cuncins |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 030309 nutrition & dietetics Medicine (miscellaneous) 030204 cardiovascular system & hematology Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Animal science Double-Blind Method Sorbitan monostearate Humans Ingestion Meals Triglycerides chemistry.chemical_classification 0303 health sciences Meal Cross-Over Studies Nutrition and Dietetics Fatty acid Postprandial Period Dietary Fats Palm stearin Postprandial chemistry Emulsions Particle size Chylomicron |
| Zdroj: | The Journal of Nutrition. 150:64-72 |
| ISSN: | 0022-3166 |
| DOI: | 10.1093/jn/nxz207 |
| Popis: | BACKGROUND The presence of triacylglycerol (TAG) cystallinity is assumed to influence digestibility and postprandial lipemia (PPL), although studies to date are limited. OBJECTIVE This study aimed to investigate whether the presence of solid fat compared with undercooled liquid oil, specifically, plays a role in determining PPL by comparing emulsion droplets differing only in terms of physical state. METHODS Ten percent palm stearin and 0.4% sorbitan monostearate emulsions were tempered to contain identically sized, charged, and shaped (spherical) undercooled liquid (LE) compared with partially crystalline solid (SE; mean ± SEM: 33.2% ± 0.03% solid fat at 37°C) droplets. Fifteen healthy fasting adult men (mean ± SD age: 27.5 ± 5.7 y; BMI: 24.1 ± 2.5 kg/m2) consumed 500 mL of each emulsion on separate occasions and plasma TAG concentrations, particle size of the plasma chylomicron-rich fraction (CMRF), and fatty acid (FA) composition of the CMRF-TAG were serially determined in a 6-h postprandial randomized double-blind crossover acute meal study. Changes from baseline values were analyzed by repeated-measures ANOVA. RESULTS An earlier (2 compared with 3 h, P |
| Databáze: | OpenAIRE |
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