Use of Etests with carbapenems for Gram-negative rods producing beta-lactamases
| Autor: | Ümit Arabaci, Bekir Kocazeybek |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Imipenem Gram-negative bacteria Microbial Sensitivity Tests Biology medicine.disease_cause Meropenem beta-Lactamases Microbiology Enterobacteriaceae Species Specificity Drug Resistance Multiple Bacterial polycyclic compounds medicine Gram-negative rods Humans Pharmacology (medical) Etest Antibacterial agent Pseudomonas aeruginosa β lactamases General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Infectious Diseases Gram-Negative Aerobic Rods and Cocci bacteria Thienamycins Pseudomonadaceae medicine.drug |
| Zdroj: | International journal of antimicrobial agents. 19(2) |
| ISSN: | 0924-8579 |
| Popis: | The in vitro activity of imipenem and meropenem on strains of Gram-negative rods producing extended-spectrum β-lactamase (ESBL) and inducible β-lactamase (IBL) was studied using the Etest. In all, 185 strains from the surgical intensive care units of four different hospitals were looked at over 2 years. Of these, 94 were ESBL producers and 91 were IBL positive. The in vitro sensitivities of imipenem and meropenem were 89.7 and 95.1%, respectively, against all strains. The imipenem and meropenem sensitivities of Klebsiella spp. were 98.4 and 100%, respectively, but imipenem resistance (21.6%) in Pseudomonas aeruginosa strains was higher than that of meropenem (10.8%). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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