| Autor: |
Bartmann, Catharina, Raman, Sudha Janaki, Flöter, Jessica, Schulze, Almut, Bahlke, Katrin, Willingstorfer, Jana, Strunz, Maria, Wöckel, Achim, Klement, Rainer, Kapp, Michaela, Cholpon Djuzenova, Otto, Christoph, Kämmerer, Ulrike |
| Rok vydání: |
2018 |
| DOI: |
10.6084/m9.figshare.6487841 |
| Popis: |
Columns represent mean ± SEM of cell proliferation after irradiation shown for the seven cell lines at 21% and 5% oxygen concentration (gray column = with 3-OHB; black column without 3-OHB) (summarized in Fig. 6). The BT20, BT474 and T47D cell lines cultured in the presence of 3-OHB showed a trend towards increased radio-resistance at 21% oxygen (with some significant results at single doses). In contrast, in MCF-7 and MDA-MB 468, 3-OHB cultured cells showed a trend towards impaired cell proliferation following radiation at the same oxygen concentration. At 5% oxygen concentration, 3-OHB seemed to have a sensitizing effect to radiation in some cell lines. Columns represent mean ± SEM of 3 independent experiments with 6 replicate wells per experiment. * |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
