Clinical pharmacology of cancer therapies in older adults

Autor:	S M Lichtman, Arti Hurria
Rok vydání:	2008
Předmět:	Aging Cancer Research medicine.medical_specialty Cancer therapy Reviews Antineoplastic Agents law.invention 03 medical and health sciences older patient 0302 clinical medicine Pharmacokinetics law medicine Humans 030212 general & internal medicine geriatric oncology skin and connective tissue diseases Intensive care medicine Aged Aged 80 and over Geriatrics Clinical Trials as Topic Clinical pharmacology business.industry Extramural Cancer medicine.disease 3. Good health Surgery Oncology Geriatric oncology 030220 oncology & carcinogenesis cancer therapy sense organs business pharmacokinetics
Zdroj:	British Journal of Cancer
ISSN:	1532-1827 0007-0920
DOI:	10.1038/sj.bjc.6604201
Popis:	This abbreviated review outlines the physiologic changes associated with aging, and examines how these changes may affect the pharmacokinetics and pharmacodynamics of anticancer therapies. We also provide an overview of studies that have been conducted evaluating the pharmacology of anticancer therapies in older adults, and issue a call for further research.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39bec22cd8536a001d9b1cd32685453 https://doi.org/10.1038/sj.bjc.6604201 Zobrazit plný text záznamu Plný text ve formátu PDF