Retrospective analysis of oral peripheral nerve sheath tumors in Brazilians
| Autor: | Ricardo Alves Mesquita, Juliana Tito Salla, Maria Cássia Ferreira de Aguiar, Bruna Gonçalves Garcia, Aline Cristina Batista Rodrigues Johann |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Epidemiology Biopsy Malignant peripheral nerve sheath tumor Young Adult Neuroma Oral and maxillofacial pathology medicine Humans Neurofibroma General Materials Science Child Solitary neurofibroma Aged Retrospective Studies Traumatic neuroma Aged 80 and over Mouth business.industry S100 Proteins Palisaded encapsulated neuroma Middle Aged medicine.disease Immunohistochemistry lcsh:RK1-715 lcsh:Dentistry Nerve sheath neoplasms Female Mouth Neoplasms business Brazil Nerve sheath neoplasm |
| Zdroj: | Brazilian Oral Research, Vol 23, Iss 1, Pp 43-48 (2009) Brazilian Oral Research v.23 n.1 2009 Brazilian Oral Research Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO Brazilian Oral Research, Volume: 23, Issue: 1, Pages: 43-48, Published: MAR 2009 |
| ISSN: | 1806-8324 |
| Popis: | Traumatic neuroma, neurofibroma, neurilemmoma, palisaded encapsulated neuroma and malignant peripheral nerve sheath tumor (MPNST) are peripheral nerve sheath tumors and present neural origin. The goal of this study was to describe the epidemiological data of oral peripheral nerve sheath tumors in a sample of the Brazilian population. Biopsies requested from the Oral Pathology Service, School of Dentistry, Federal University of Minas Gerais (MG, Brazil), between 1966 and 2006 were evaluated. Lesions diagnosed as peripheral nerve sheath tumors were submitted to morphologic and to immunohistochemical analyses. All cases were immunopositive to the S-100 protein. Thirty-five oral peripheral nerve sheath tumors were found, representing 0.16% of all lesions archived in the Oral Pathology Service. Traumatic neuroma (15 cases) most frequently affected the mental foramen. Solitary neurofibroma (10 cases) was more frequently observed in the palate. Neurofibroma associated with neurofibromatosis type I (2 cases) was observed in the gingival and alveolar mucosa. Neurilemmoma (4 cases) was more commonly observed in the buccal mucosa. Malignant peripheral nerve sheath tumors (3 cases) occurred in the mandible, palate, and tongue. Palisaded encapsulated neuroma (1 case) occurred in the buccal mucosa. The data confirmed that oral peripheral nerve sheath tumors are uncommon in the oral region, with some lesions presenting a predilection for a specific gender or site. This study may be useful in clinical dentistry and oral pathology practice and may be used as baseline data regarding oral peripheral nerve sheath tumors in other populations. |
| Databáze: | OpenAIRE |
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