Expedient Total Syntheses of WIN 64745 and WIN 64821

Autor: Carlos Pérez-Balado, Angel R. de Lera
Rok vydání: 2008
Předmět:
Zdroj: Organic Letters. 10:3701-3704
ISSN: 1523-7052
1523-7060
DOI: 10.1021/ol8013073
Popis: Bispyrrolidinoindoline diketopiperazine alkaloids were synthesized from a common intermediate in seven steps from commercially available amino acids. This versatile synthetic strategy has led to the accomplishment of the first total synthesis of heterodimeric WIN 64745 and a novel approach to homodimeric WIN 64821.
Databáze: OpenAIRE