Diffuse perfusion abnormality of the liver parenchyma on angiography-assisted helical CT in relation to cirrhosis and previous treatments: a potential diagnostic pitfall for detecting hepatocellular carcinoma
| Autor: | Yoshiharu Nakayama, Yasuyuki Yamashita, Katsuhiko Mitsuzaki, Michio Ando, Akihiko Arakawa, Tomohiro Namimoto, Mutsumasa Takahashi, Osamu Makita, Yoichi Oyama |
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| Rok vydání: | 2001 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Cirrhosis Carcinoma Hepatocellular Collateral Circulation Hepatic Artery Parenchyma Carcinoma Medicine Humans Radiology Nuclear Medicine and imaging Chemoembolization Therapeutic Portography Aged medicine.diagnostic_test business.industry Liver Neoplasms medicine.disease Collateral circulation Liver Hepatocellular carcinoma Angiography Female Radiology business Tomography X-Ray Computed Perfusion |
| Zdroj: | Clinical imaging. 24(5) |
| ISSN: | 0899-7071 |
| Popis: | We evaluated diffuse perfusion abnormality of the liver parenchyma in relation to cirrhosis and previous treatments and estimated its potential limitation in detecting hepatocellular carcinomas (HCCs) on CT arterial portography (CTAP) and CT hepatic arteriography (CTHA). Sixty-one patients of liver cirrhosis with or without HCC received both CTAP and CTHA. Irregular defects of enhancement of the liver parenchyma on CTAP were noted in 37 of 61 patients (60.7%) and compensatory arterial perfusion in these defects on CTHA was noted in 30 of 37 patients (81.1%). Most patients had segmental or mixed patterns of enhancement. In patients with severe cirrhosis, irregular enhancement was often noted. The irregularity was also more often in patients who had had previous treatments. Four of 40 HCC nodules in 18 patients with severe irregular perfusion were not detected on CTAP and CTHA. Diffuse perfusion abnormalities of the liver parenchyma on CTAP and CTHA would decrease the accuracy of tumor detection in HCC patients. |
| Databáze: | OpenAIRE |
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