Ventricular-vascular coupling in hypertension: methodological considerations and clinical implications
| Autor: | Saba, Ps, Cameli, M, Casalnuovo, G, Ciccone, Mm, Ganau, A, Maiello, M, Modesti, Pa, Muiesan, Ml, Novo, S, Palmiero, P, Sanna, Gd, Schicchitano, P, Pedrinelli, Roberto, On behalf of the Working Group on Hypertension, Prevention, Rehabilitation of the Italian Society of Cardiology |
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| Přispěvatelé: | Saba, PS, Cameli, M, Casalnuovo, G, Ciccone, MM, Ganau, A, Maiello, M, Modesti, PA, Muiesan, ML, Novo, S, Palmiero, P, Sanna, GD, Schicchitano, P, Pedrinelli, R |
| Rok vydání: | 2014 |
| Předmět: |
Ventricular-vascular coupling
medicine.medical_specialty Wave reflection Heart Ventricles Left Diastole Blood Pressure Left ventricular hypertrophy Pulse wave analysis Ventricular Function Left Input impedance Vascular Stiffness Effective arterial elastance Internal medicine medicine Ventricular Function Humans Arterial stiffness Hypertension Therapy Aorta Arteries Elasticity Cardiology and Cardiovascular Medicine Medicine (all) Arterial structure Ventricular function business.industry arterial stiffness effective arterial elastance hypertension input impedance left ventricular hypertrophy pulse wave analysis therapy ventricular–vascular coupling wave reflection General Medicine medicine.disease Settore MED/11 - Malattie Dell'Apparato Cardiovascolare Arterial tree medicine.anatomical_structure Ventricle Cardiology business Ventricular vascular coupling |
| Zdroj: | Journal of cardiovascular medicine (Hagerstown, Md.). 15(11) |
| ISSN: | 1558-2035 |
| Popis: | The present review is addressed to analyse the complex interplay between left ventricle and arterial tree in hypertension. The different methodological approaches to the analysis of ventricular vascular coupling in the time and frequency domain are discussed. Moreover, the role of hypertension-related changes of arterial structure and function (stiffness and wave reflection) on arterial load and how ventricular-vascular coupling modulates the process of left ventricular adaptation to hypertension are analysed.The different interplay between vascular bed and left ventricle emerges as the pathophysiological basis for the development of the multiple patterns of ventricular structural adaptation in hypertension and provides a pathway for the interpretation of systolic and diastolic functional abnormalities observed in hypertensive patients. Targeting the therapeutic approach to improve ventricular-vascular coupling may have relevant impact on reversing left ventricular hypertrophy and improving systolic and diastolic dysfunction. |
| Databáze: | OpenAIRE |
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