Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site

Autor: Yuyang Liu, Zeyuan He, Wen Ma, Guangjun Bao, Yiping Li, Changjun Yu, Jingyue Li, Ruiyao E, Zhaoqing Xu, Rui Wang, Wangsheng Sun
Rok vydání: 2022
Předmět:
Zdroj: Organic Letters. 24:9248-9253
ISSN: 1523-7052
1523-7060
DOI: 10.1021/acs.orglett.2c03813
Popis: We have developed a method of introducing biological oxime ether fragments into peptides by CuI-catalyzed late-stage modification and functionalization of peptides, utilizing their acid moiety and varied 2
Databáze: OpenAIRE