New Developments in the Staging of Melanoma
Autor: | Jiaqi Shi, Amy C. Baruch, Yongmei Feng, Mark A. Nelson |
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Rok vydání: | 2005 |
Předmět: |
Proteomics
Cancer Research Skin Neoplasms CDNA Arrays Reverse Transcriptase Polymerase Chain Reaction Extramural Melanoma General Medicine Disease Biology medicine.disease Bioinformatics Oncology Biomarkers Tumor medicine Humans Human melanoma Neoplasm staging Neoplasm Staging Oligonucleotide Array Sequence Analysis |
Zdroj: | Cancer Investigation. 23:561-567 |
ISSN: | 1532-4192 0735-7907 |
Popis: | As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. The application of molecular techniques may provide powerful new tools in this search. This review summarizes recent findings obtained by means of conventional RT-PCR, cDNA arrays, and proteomics in the investigation of human melanoma. The molecular tools discussed in this review demonstrate how global transcript and protein analysis might contribute not only to the staging of melanoma, but may hold great promise in improving the diagnosis and treatment of this disease. |
Databáze: | OpenAIRE |
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