The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues
| Autor: | Sally L. Goodwin, Mary M. Kurien, Mark A. Stewart, William R. Sherman |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Male
Tissue concentrations Chromatography Gas Chemical Phenomena Biophysics Kidney Biochemistry Nervous System chemistry.chemical_compound Lens Crystalline Testis Animals Inositol Molecular Biology Pancreas Hexoses Muscles food and beverages Myo-inosose Rats carbohydrates (lipids) Chemistry chemistry Adipose Tissue Liver Tissue extracts lipids (amino acids peptides and proteins) Rabbits Spleen scyllo-Inositol |
| Zdroj: | Biochimica et biophysica acta. 158(2) |
| ISSN: | 0006-3002 |
| Popis: | While myo -inosose-2 has been postulated to be an intermediate in the conversion of myo - to scyllo -inositol, this cyclose has only recently been observed as a naturally occurring tissue component. We present in this paper the first measured levels of myo -inosose-2 in biological tissues. We also present for the first time the concentrations of scyllo -inositol in mammalian organs. Myo -inositol, myo -inosose-2 and scyllo -inositol are here measured in organs of the rat and rabbit chromatography of trimethylsilylated tissue extracts. The millimolar tissue levels of myo -inositol and scyllo -inositol are measured by a hydrogen flame ionization detector, and the micromolar tissue concentrations of myo -inosose-2 by an electron capture detector. The simultaneous occurrence of myo -inositol, scyllo -inositol and myo -inosose-2 in many tissues supports tha metabolic interrelationship of these three cyclitols, a situation which has been postulated in the past by others. |
| Databáze: | OpenAIRE |
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