Are we ready for a gender-specific approach in interventional cardiology?
| Autor: | Calabrò, P, Niccoli, G, Gragnano, F, Grove, El, Vergallo, R, Mikhailidis, Dp, Patti, G, Spaccarotella, C, Katsiki, N, Masiero, G, Ueshima, D, Pinar, E, Chieffo, A, Ussia, Gp, Eitel, I, Tarantini, G, Working Group of Interventional Cardiology of the Italian Society of, Cardiology. |
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| Přispěvatelé: | Calabrò, Paolo, Niccoli, Giampaolo, Gragnano, Felice, Grove, Erik Lerkevang, Vergallo, Rocco, Mikhailidis, Dimitri P., Patti, Giuseppe, Spaccarotella, Carmen, Katsiki, Niki, Masiero, Giulia, Ueshima, Daisuke, Pinar, Eduardo, Chieffo, Alaide, Ussia, Gian Paolo, Eitel, Ingo, Tarantini, Giuseppe, Calabro, P., Niccoli, G., Gragnano, F., Grove, E. L., Vergallo, R., Mikhailidis, D. P., Patti, G., Spaccarotella, C., Katsiki, N., Masiero, G., Ueshima, D., Pinar, E., Chieffo, A., Ussia, G. P., Eitel, I., Tarantini, G. |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Interventional cardiology Mitral valve annuloplasty Percutaneous coronary intervention Transcatheter aortic valve replacement Women gender Cardiology and Cardiovascular Medicine medicine.medical_treatment Cardiovascular Surgical Procedure Cardiology Disease 030204 cardiovascular system & hematology Global Health Risk Assessment Coronary artery disease 03 medical and health sciences 0302 clinical medicine Sex Factors Risk Factors Internal medicine Cardiovascular Disease medicine gender Humans Women 030212 general & internal medicine Sex Distribution Mitral valve repair business.industry Cardiovascular Surgical Procedures Risk Factor valvular heart disease medicine.disease Cardiovascular Diseases Female Morbidity business Percutaneous Mitral Valve Repair Human |
| Zdroj: | Calabrò, P, Niccoli, G, Gragnano, F, Grove, E L, Vergallo, R, Mikhailidis, D P, Patti, G, Spaccarotella, C, Katsiki, N, Masiero, G, Ueshima, D, Pinar, E, Chieffo, A, Ussia, G P, Eitel, I, Tarantini, G & Working Group of Interventional Cardiology of the Italian Society of Cardiology 2019, ' Are we ready for a gender-specific approach in interventional cardiology? ', International Journal of Cardiology, vol. 286, no. July, pp. 226-233 . https://doi.org/10.1016/j.ijcard.2018.11.022 |
| DOI: | 10.1016/j.ijcard.2018.11.022 |
| Popis: | Gender differences in the pathophysiology of atherosclerosis, cardiovascular risk factors, and diagnosis of coronary artery disease and valvular heart disease are well known. Such differences have also been outlined in the management and outcomes after acute coronary syndromes and valvular repair. Regarding the atherosclerotic process, pathological experimental studies suggest that plaque composition and burden may differ by gender. Female gender is associated with worse outcomes in the case of ischemic heart disease and, compared with men, women are less likely to undergo interventional cardiac procedures and sustain worse outcomes. In the setting of valvular heart disease (VHD), transcatheter aortic valve implantation (TAVI) and percutaneous edge-to-edge mitral valve repair are now well-established procedures with high success rates. In women with moderate to severe aortic stenosis, subgroup analyses in TAVI trials have demonstrated gender-related differences suggesting female gender as beneficial in terms of short-, mid-, and long-term outcomes. Similarly, several studies reported different procedural challenges and outcomes in males and females following surgical and percutaneous mitral valve repair. These diverse findings emphasize the necessity to provide gender-specific analyses of interventional methods. This review highlights gender differences in the epidemiology, pathophysiology, treatment options and clinical outcomes of the conditions mentioned above. |
| Databáze: | OpenAIRE |
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