Mineralocorticoid receptor blockade improves pulmonary hypertension and right ventricular function in bronchopulmonary dysplasia: a case report
| Autor: | Georg Hansmann, Roberto Giagnorio |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Prohormone 030204 cardiovascular system & hematology medicine.disease Brain natriuretic peptide Pulmonary hypertension Blockade 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Hydrochlorothiazide Mineralocorticoid receptor 030228 respiratory system Bronchopulmonary dysplasia chemistry Internal medicine medicine Spironolactone Cardiology Cardiology and Cardiovascular Medicine business Case Report on Right Ventricular Dysfunction medicine.drug |
| Zdroj: | Cardiovasc Diagn Ther |
| ISSN: | 2223-3660 2223-3652 |
| DOI: | 10.21037/cdt.2020.02.05 |
| Popis: | Bronchopulmonary dysplasia (BPD) is a combined pulmonary vascular and parenchymal disease, representing the most common cause of chronic lung disease (CLD) in infancy. Pulmonary hypertension (PH) is frequently associated with BPD and—if persistent—substantially increases mortality. We report on a 4-month-old, former preterm infant with BPD, severe PH and right heart failure who greatly and rapidly improved clinical status and right ventricular (RV) function by means of blood biomarkers [N-terminal prohormone of brain natriuretic peptide (NT-pro-BNP), cardiac troponin T] and transthoracic echocardiography, following the addition of spironolactone and hydrochlorothiazide to the treatment regimen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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