Utilidad de las tiras reactivas para el diagnóstico temprano de Peritonitis Bacteriana Espontánea en pacientes cirróticos
| Autor: | Bejarano Rengifo, Janeth |
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| Přispěvatelé: | Garzón Olarte, Martín Alonso |
| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2017 |
| Předmět: | |
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| Popis: | Introducción. La peritonitis bacteriana espontánea (PBE) requiere un diagnóstico temprano para el inicio de antibioticoterapia. El diagnóstico se basa en el estudio citoquímico del líquido ascítico, éste toma horas para su realización y tiene disponibilidad limitada las 24 horas, particularmente, en hospitales de primer nivel y en zonas rurales. Evaluamos la utilidad y precisión diagnóstica de las tiras reactivas Multistix 10SG para el diagnóstico de PBE en pacientes cirróticos con ascitis atendidos en la Fundación Cardioinfantil-Instituto de Cardiología. Materiales y métodos. Estudio de prueba diagnóstica. Se determinó el conteo de leucocitos del líquido ascítico por la escala colorimétrica de la tira reactiva Multistix 10SG y se comparó con el gold standard para el diagnóstico de PBE (polimorfonucleares ≥ 250 células/mm³. Resultados. De 106 pacientes con ascitis (51.8% hombres, promedio de edad 59 años) 16 fueron diagnosticados con PBE. Con un punto de corte grado ++, la tira reactiva tuvo sensibilidad 93.7%, especificidad 95.5%, valor predictivo positivo 78.9%, valor predictivo negativo 98%, razón de probabilidad positiva 21 y razón de probabilidad negativa 0.06. Conclusiones. La tira reactiva Multistix 10SG tiene una alta sensibilidad y especificidad para el diagnóstico de PBE comparada con el método de conteo de PMN. Es una técnica de bajo costo, fácil de realizar, requiere de un tiempo mínimo para su interpretación y está ampliamente disponible, incluso en áreas remotas. Éste test puede ser útil para el abordaje diagnóstico de PBE en un país como Colombia. Introduction. Spontaneous bacterial peritonitis (SBP) requires an early diagnosis for the initiation of antibiotic therapy. The diagnosis is based on cytochemical examination of ascitic fluid, which takes hours to perform and has limited availability 24 hours a day, especially in first level hospitals and in rural areas. We evaluated the utility and diagnostic accuracy of Multistix 10SG reagent strip for diagnosis of SBP in cirrhotic patients with ascites admitted in Cardioinfantil Foundation –Cardiology Institute. Materials and methods. Diagnostic test study in cirrhotic patients with ascites. The leucocyte count of ascitic fluid was determined by colorimetric scale of Multistix 10SG reagent strips and was compared with the gold standard for the diagnosis of SBP (polymorphonuclear (PMN) ≥ 250 cells / mm³). Results. Of 106 patients with ascites (51.8% men, mean age 59 years) 16 patients were diagnosed with SBP. The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio taking grade ++ as cut off were 93.7%, 95.5%, 78.9%, 98%, 21 and 0.06, respectively. Conclusions. Multistix 10SG reagent strip has a high sensitivity and specificity for the diagnosis of PBE compared to PMN count method. It is a inexpensive and easy technique, requires minimal time for interpretation and is available, even in remote areas. This test may be useful for the diagnosis of SBP in country like Colombia 2020-12-12 01:01:02: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2020-12-11 |
| Databáze: | OpenAIRE |
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