Comparison of 50 μg and 25 μg doses of intrathecal morphine on postoperative analgesic requirements in patients undergoing transurethral resection of the prostate with intrathecal anesthesia
| Autor: | Mehmet Balasar, Recai Gürbüz, Seza Apiliogullari, Murat Karcioglu, Ates Duman |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Vomiting medicine.medical_treatment Analgesic Group B Intrathecal morphine Double-Blind Method medicine Humans In patient Prospective Studies Anesthetics Local Injections Spinal Antipruritic Aged Transurethral resection of the prostate Bupivacaine Pain Postoperative Dose-Response Relationship Drug Morphine business.industry Transurethral Resection of Prostate Middle Aged Surgery Analgesics Opioid Anesthesiology and Pain Medicine Patient Satisfaction Anesthesia business medicine.drug |
| Zdroj: | Journal of Clinical Anesthesia. 22:329-333 |
| ISSN: | 0952-8180 |
| DOI: | 10.1016/j.jclinane.2009.09.006 |
| Popis: | Study Objective To compare the efficacy of 50 μ g and 25 μ g doses of intrathecal morphine on postoperative pain in patients undergoing transurethral resection of the prostate (TURP) with low-dose bupivacaine. Design Randomized, double-blinded study. Setting Konya Hospital. Patients 70 ASA physical status I, II, and III patients. Interventions Patients were randomized to two groups: Group A patients received 5 mg of 0.5% hyperbaric bupivacaine (one mL) and 50 μ g of morphine (0.5 mL). Group B patients received 5 mg of 0.5% hyperbaric bupivacaine (one mL) and 25 μ g of morphine (0.5 mL). Measurements Postoperative pain scores, patient and surgeon satisfaction, and side effects such as emesis, pruritus, and respiratory depression, were recorded. Main Results Postoperative pain characteristics were similar between the two groups. Frequency of emesis was similar between the groups, while pruritus was significantly higher in Group A. No antipruritic medication was required in any patient. Patient and surgeon satisfaction was evaluated as good or excellent in both groups. Conclusions Intrathecal morphine at a dose of 25 μ g provides similar postoperative analgesia and less pruritus than the 50 μ g dose in patients undergoing TURP. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect