Improving newborn skin health: Effects of diaper care regimens on skin pH and erythema
| Autor: | Jennifer Gustin, Julie Ogle, Marty O. Visscher, Lisa Bohman, Andrew N. Carr, Vivek Narendran, Maria C. Mitchell, Gina M. Fadayel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
diaper skin
medicine.medical_specialty Diaper Dermatitis Erythema Dermatology Perianal space neonatal skin 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Humans Skin Cross-Over Studies integumentary system business.industry Infant Newborn Infant Diapering Original Articles Hydrogen-Ion Concentration Skin Care Infant newborn Crossover study Regimen Skin irritation Diaper Rash 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Original Article medicine.symptom business skin pH diaper dermatitis |
| Zdroj: | Pediatric Dermatology |
| ISSN: | 1525-1470 0736-8046 |
| Popis: | Background/Objective Newborn infant skin is functional but immature, and diapering products can play a significant role in infant diapered skin health. Previous work demonstrated a regimen consisting of a diaper with an emollient and apertures on the inner liner (topsheet) with an acidic, pH‐buffered wipe (Regimen A) lowered newborn skin pH and reduced the enzymatic activity on skin post‐stool cleaning versus a regimen without these features (Regimen B). This study extends these findings to determine the impact of Regimen A on diaper area erythema severity over a 2‐week use period. Methods This IRB‐approved, blinded, randomized, crossover study enrolled newborn infants >7 days and ≤8 weeks. Participants exclusively used two unique diaper and wipe combinations, Regimen A and Regimen B (non‐emollient, non‐aperture containing topsheet and wipe with limited buffering capacity), each for 14 days and preceded by a 3‐day washout regimen. Results Diapered skin pH was reduced during Regimen A use to values similar to that of a non‐diapered control site (chest), while use of Regimen B was associated with a more alkaline skin pH. Regimen A resulted in significantly fewer severe erythema episodes. At the site of highest erythema, the perianal space, the average erythema score was significantly lower and more newborns were free of erythema while using Regimen A vs. Regimen B (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text