Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy

Autor:	Fawad Ur Rehman, Yang Liu, Qingshan Yang, Haoying Yang, Runhan Liu, Dongya Zhang, Pir Muhammad, Yanjie Liu, Sumaira Hanif, Muhammad Ismail, Meng Zheng, Bingyang Shi
Rok vydání:	2021
Předmět:	Brain Neoplasms Drug Resistance Neoplasm Cell Line Tumor Temozolomide Pharmaceutical Science Humans RNA Small Interfering Exosomes Glioblastoma Antineoplastic Agents Alkylating Xenograft Model Antitumor Assays Heme Oxygenase-1
Zdroj:	Journal of controlled release : official journal of the Controlled Release Society. 345
ISSN:	1873-4995
Popis:	Glioblastoma (GBM) is a highly fatal and recurrent brain cancer without a complete prevailing remedy. Although the synthetic nanotechnology-based approaches exhibit excellent therapeutic potential, the associated cytotoxic effects and organ clearance failure rest major obstacles from bench to clinics. Here, we explored allogeneic bone marrow mesenchymal stem cells isolated exosomes (BMSC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35f309306ff705765fe9f39058560bb https://pubmed.ncbi.nlm.nih.gov/35341901 Zobrazit plný text záznamu Full Text from ScienceDirect