Value of Combined Detection of Serum CEA, CA72-4, CA19-9 and TSGF in the Diagnosis of Gastric Cancer
| Autor: | Dong-Zhen Mou, Li-Kui Yin, Xue-Qing Sun |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Pathology Optimal cutoff CA-19-9 Antigen Epidemiology Diagnostic accuracy Physical examination Adenocarcinoma Gastroenterology Antigens Neoplasm Stomach Neoplasms Internal medicine Biomarkers Tumor medicine Humans Antigens Tumor-Associated Carbohydrate Aged Neoplasm Staging Tumor marker Aged 80 and over Receiver operating characteristic medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health Cancer Middle Aged Prognosis medicine.disease digestive system diseases Carcinoembryonic Antigen Neoplasm Proteins Survival Rate ROC Curve Oncology Case-Control Studies Female CA19-9 business Area under the roc curve Biomarkers Follow-Up Studies |
| Zdroj: | Asian Pacific Journal of Cancer Prevention. 16:3867-3870 |
| ISSN: | 1513-7368 |
| Popis: | Background: To explore whether combined detection of serum tumor markers (CEA, CA72-4, CA19-9 and TSGF) improve the sensitivity and accuracy in the diagnosis of gastric cancer (GC). Materials and Methods: An automatic chemiluminescence immune analyzer with matched kits were used to determine the levels of serum CEA, CA72-4, CA19-9 and TSGF in 45 patients with gastric cancer (GC group), 40 patients with gastric benign diseases (GBD group) hospitalized in the same period and 30 healthy people undergoing a physical examination. The values of those 4 tumor markers in the diagnosis of gastric cancer was analyzed. Results: The levels of serum CEA, CA72-4, CA19-9 and TSGF of the GC group were higher than those of the GBD group and healthy examined people and the differences were significant ( P |
| Databáze: | OpenAIRE |
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