Treatment-related cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis

Autor:	Mark Hamilton, M Grounds, N Arulkumaran, Andrews Rhodes, J Ball, Carlos Corredor, Maurizio Cecconi
Rok vydání:	2013
Předmět:	Inotrope medicine.medical_specialty Cardiac output business.industry Goal directed therapy Critical Care and Intensive Care Medicine Increased risk Postoperative mortality Meta-analysis Poster Presentation Emergency medicine medicine Augment Intensive care medicine business Surgical patients
Zdroj:	Critical Care
ISSN:	1364-8535
DOI:	10.1186/cc12133
Popis:	We hypothesized that goal-directed therapy (GDT) is not associated with an increased risk of cardiac complications in high-risk, noncardiac surgical patients. Patients with limited cardiopulmonary reserve are at risk of mortality and morbidity after major surgery [1]. Augmentation of the oxygen delivery index (DO2I) with a combination of intravenous fluids and inotropes (GDT) has been shown to reduce the postoperative mortality and morbidity in high-risk patients [2]. However, concerns regarding cardiac complications associated with fluid challenges and inotropes used to augment cardiac output may deter clinicians from instituting early GDT in the very patients who are more likely to benefit.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35a155845fb1346f83eac990179412d https://doi.org/10.1186/cc12133 Zobrazit plný text záznamu Full text from SpringerLink