Microencapsulation of Ascorbic Acid for Cosmetic by Utilizing Self-assembly of Phase Separated Polymer
| Autor: | Akito Nakai, Takashi Michida, Shiro Nakai |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Polymers
Surface Properties 02 engineering and technology Ascorbic Acid Cosmetics 01 natural sciences Polymerization Phase (matter) 0103 physical sciences Drug Discovery Solubility Particle Size chemistry.chemical_classification Chromatography 010304 chemical physics Water General Chemistry General Medicine Polymer 021001 nanoscience & nanotechnology Ascorbic acid chemistry Chemical engineering Emulsion Emulsions Particle size Self-assembly 0210 nano-technology Oils |
| Zdroj: | Chemicalpharmaceutical bulletin. 64(10) |
| ISSN: | 1347-5223 |
| Popis: | Micrometer-sized polymer particles encapsulated ascorbic acid (vitamin C; VC) were successfully prepared by the three types of the self-assembling method, those are, phase separation and self-assembly of added polymer at the oil-water interface in emulsion, microsuspension polymerization utilizing the self-assembling of phase separated polymer (SaPSeP) method, and their hybrid method. In the stability study at 50°C for 2 months, the three kinds of capsule particles exhibited effective protection of VC from the interaction with other components in cosmetic consisting of water-in-oil (W/O) emulsion. The encapsulated VC was easily released from the capsule particles by an excess of water. These encapsulation methods will be useful for the stabilization of water-soluble substances in cosmetic consisting of W/O emulsion. |
| Databáze: | OpenAIRE |
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