A focus on natural products for preventing and cure of mitochondrial dysfunction in Parkinson’s disease

Autor:	Abbas Mohammadipour
Rok vydání:	2022
Předmět:	Biological Products Oxidative Stress Cellular and Molecular Neuroscience Cell Death Humans Parkinson Disease Neurology (clinical) Biochemistry Mitochondria
Zdroj:	Metabolic Brain Disease. 37:889-900
ISSN:	1573-7365 0885-7490
Popis:	Mitochondria are considered the only source of energy production within cells. This organelle is vital for neural function and survival by producing energy (adenosine triphosphate (ATP)) and regulating intracellular calcium. Mitochondrial dysfunction, which significantly contributes to both idiopathic and familial types of Parkinson's disease (PD), depletes cellular energy, disrupts homeostasis, and induces oxidative stress, leading to cell death. In recent years several natural products have been discovered to be protective against mitochondrial dysfunction. This review discusses the role of mitochondria in the progression of PD to define the path for using natural products to prevent and/or cure PD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3425061df9d61e513ad67440e0d14bf https://doi.org/10.1007/s11011-022-00931-8 Zobrazit plný text záznamu Full text from SpringerLink