Airway smooth muscle in the pathophysiology and treatment of asthma
| Autor: | Diana C. Doeing, Julian Solway |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty Pathophysiology of asthma Physiology Inflammation Models Biological immune system diseases Physiology (medical) medicine Humans Lung Asthma business.industry Muscle Smooth Airway smooth muscle respiratory system musculoskeletal system medicine.disease Pathophysiology respiratory tract diseases medicine.anatomical_structure Immunology Bronchoconstriction medicine.symptom business Airway |
| Zdroj: | Journal of Applied Physiology. 114:834-843 |
| ISSN: | 1522-1601 8750-7587 |
| Popis: | Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is potentiated by constrictor hyperresponsiveness, impaired relaxation and length adaptation. ASM also contributes to airway remodeling and inflammation in asthma. In light of this, ASM is an important target in the treatment of asthma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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