A physical method for preservation of cosmetic products
| Autor: | K. Lintner, V. Genet |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Aging
medicine.medical_specialty Chemistry medicine.medical_treatment media_common.quotation_subject Pharmaceutical Science Dermatology Cutaneous irritation medicine.disease_cause Cosmetics Surgery Colloid and Surface Chemistry Microbiological contamination Chemistry (miscellaneous) Lotion Drug Discovery Self-healing hydrogels medicine Food science Moisturizer Irritation Challenge tests media_common |
| Zdroj: | International journal of cosmetic science. 20(2) |
| ISSN: | 0142-5463 |
| Popis: | To date, the microbiological stability of cosmetics products is assured by means of chemical preservatives, with well-known possible side effects such as irritation or cutaneous allergic events. This paper describes a new concept to protect all types of cosmetic formulae from microbiological contamination: the osmotic effect of a particular form of glycerylpolyacrylate gels. The latter allows the formulator to conceive numerous preservative-free formulae. The basis of its activity lies in the strong osmotic properties of the hydrogel: it absorbs water from its surroundings, thus depriving germs of the vital aqueous environment needed for survival. Challenge tests on various microorganisms, repeat insult challenges and time-stability tests performed on these hydrogels in cosmetic formulas were carried out. At the same time, the hydrogel exhibited high skin moisturizing power. The hydrogel is non-toxic and non-irritant as the Primary Cutaneous Irritation Index observed after 48 h of occlusive patches in 10 adult volunteers is only of 0.10. |
| Databáze: | OpenAIRE |
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