Matrix proteins plug a hole: How pericytes suppress blood brain barrier transcytosis

Autor:	Troy N, Trevino, Sarah E, Lutz
Rok vydání:	2022
Předmět:	Blood-Brain Barrier General Neuroscience Brain Endothelial Cells Biological Transport Pericytes Transcytosis
Zdroj:	Neuron. 110:1601-1603
ISSN:	0896-6273
DOI:	10.1016/j.neuron.2022.04.011
Popis:	How is the brain so efficient at excluding proteins, drugs, and immune cells from the blood? In this issue of Neuron, Ayloo et al. (2022) find that an extracellular matrix protein secreted by CNS pericytes shuts down endocytic transport in blood brain barrier endothelial cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33b4f69e89dd4c4ec887c60c5250202 https://doi.org/10.1016/j.neuron.2022.04.011 Zobrazit plný text záznamu