Effects of pendant-like hydrophilic monomers on the adsorption properties of reversed-phase-type sorbents for solid-phase extraction
| Autor: | Takashi Sugita, Yukihiro Esaka, Norio Teshima, Yuta Miki, Hiroki Tomita, Yoshinori Inoue, Hiroya Murakami, Takuya Aoyanagi |
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| Rok vydání: | 2019 |
| Předmět: |
Chemistry
010401 analytical chemistry Extraction (chemistry) Uracil 02 engineering and technology 021001 nanoscience & nanotechnology Divinylbenzene 01 natural sciences Biochemistry Diluent 0104 chemical sciences Analytical Chemistry Partition coefficient chemistry.chemical_compound Adsorption Copolymer Environmental Chemistry Solid phase extraction 0210 nano-technology Spectroscopy Nuclear chemistry |
| Zdroj: | Analytica chimica acta. 1075 |
| ISSN: | 1873-4324 |
| Popis: | Solid-phase extraction (SPE) has been extensively employed as a pretreatment method. In SPE, reversed-phase-type sorbents have been widely applied for the pretreatment of environmental or biological samples. Hydrophilic-lipophilic balance (HLB)-type sorbents, constituting the copolymers used as reversed-phase-type sorbents, have been applied for various sample pretreatment methods. In HLB-type sorbents, the hydrophilic monomer contributes to the improved wettability of sorbents and increase of polar interactions. In this study, three pendant-like hydrophilic monomers, viz. N-vinylpyrrolidone (NVP), 4-acryloylmorpholine (AMO), and 4-vinyl-1,3-dioxolan-2-one (VDO), respectively, exhibiting different Log P values and possibly causing different polar interactions, were selected to improve the adsorption properties of polar compounds, and divinylbenzene (DVB)-based HLB-type sorbents containing each hydrophilic monomer were synthesized and examined. By the optimization of the molar ratio of DVB and the hydrophilic monomer (i.e. HLB), the inert diluent, and the degree of cross-linking, the developed sorbents exhibited higher recoveries for various polar compounds (viz. cytosine, uracil, cytidine, uridine, 2'-deoxycytidine, 2'-deoxyguanosine, adenine, thymidine, adenosine, and 2'-deoxyadenosine) compared to commercially available HLB-type sorbents. |
| Databáze: | OpenAIRE |
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