Human Immunodeficiency Virus Glycoproteins: Lectin Binding Properties
| Autor: | Bror Morein, Lena Marmstål Hammar, Sigrid Eriksson |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Glycoconjugate
Immunology Biotin HIV Antibodies Virus Cell Line HIV Envelope Protein gp160 law.invention Immune system Antigen Viral envelope law Lectins Virology Humans Protein Precursors Glycoproteins chemistry.chemical_classification Vaccines biology Antibodies Monoclonal Gene Products env virus diseases Lectin Recombinant Proteins Infectious Diseases chemistry Chromatography Gel HIV-1 biology.protein Recombinant DNA Electrophoresis Polyacrylamide Gel Glycoprotein |
| Zdroj: | AIDS Research and Human Retroviruses. 5:495-506 |
| ISSN: | 1931-8405 0889-2229 |
| DOI: | 10.1089/aid.1989.5.495 |
| Popis: | Recombinant glycoproteins derived from the HIV env gene are available and are under evaluation as antigens in vaccines against AIDS. The importance of the glycoconjugate structure for eliciting a protective immune response by these proteins is incompletely known. In this report we devise a method for the characterization of the glycoconjugate and demonstrate gross differences in the composition of the carbohydrate moiety in glycoproteins derived from the HIV env gene when expressed in different cell lines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|