Aging with multimorbidity: A systematic review of the literature
Autor: | Laura Fratiglioni, Bettina Meinow, René J. F. Melis, Francesca Mangialasche, Sara Angleman, Anita Karp, Alessandra Marengoni, Annika Garmen |
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Rok vydání: | 2011 |
Předmět: |
Gerontology
Aging Cross-sectional study MEDLINE Comorbidity Biochemistry Perception and Action Alzheimer Centre [DCN 1] Scientific evidence Risk Factors Health care Animals Humans Multimorbidity Medicine Molecular Biology Socioeconomic status Quality of Health Care business.industry Incidence (epidemiology) medicine.disease Cross-Sectional Studies Neurology Chronic Disease Quality of Life business Biotechnology |
Zdroj: | Ageing Research Reviews, 10, 430-439 Ageing Research Reviews, 10, 4, pp. 430-439 |
ISSN: | 1568-1637 |
Popis: | Item does not contain fulltext A literature search was carried out to summarize the existing scientific evidence concerning occurrence, causes, and consequences of multimorbidity (the coexistence of multiple chronic diseases) in the elderly as well as models and quality of care of persons with multimorbidity. According to pre-established inclusion criteria, and using different search strategies, 41 articles were included (four of these were methodological papers only). Prevalence of multimorbidity in older persons ranges from 55 to 98%. In cross-sectional studies, older age, female gender, and low socioeconomic status are factors associated with multimorbidity, confirmed by longitudinal studies as well. Major consequences of multimorbidity are disability and functional decline, poor quality of life, and high health care costs. Controversial results were found on multimorbidity and mortality risk. Methodological issues in evaluating multimorbidity are discussed as well as future research needs, especially concerning etiological factors, combinations and clustering of chronic diseases, and care models for persons affected by multiple disorders. New insights in this field can lead to the identification of preventive strategies and better treatment of multimorbid patients. (C) 2011 Elsevier B.V. All rights reserved. |
Databáze: | OpenAIRE |
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