Palmitoylation of the influenza a virus M2 protein
| Autor: | R.B. Belshe, Alan J. Hay, R.J. Sugrue |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Viral matrix protein
Molecular Sequence Data Orthomyxoviridae Palmitic Acid Chick Embryo Palmitic Acids Biology medicine.disease_cause biology.organism_classification Virus Molecular Weight Viral Matrix Proteins Viral envelope Palmitoylation Biochemistry Influenza A virus Sequence Homology Nucleic Acid Virology medicine Animals Amino Acid Sequence Peptide sequence Cysteine |
| Zdroj: | Virology. 179:51-56 |
| ISSN: | 0042-6822 |
| DOI: | 10.1016/0042-6822(90)90272-s |
| Popis: | The M2 proteins of a variety of influenza A viruses of different subtypes were shown to possess associated palmitate. Susceptibility to removal by reduction or treatment with hydroxylamine is consistent with attachment via a thioester linkage to cysteine. The absence of the acyl group from the M2 proteins of several equine viruses of the H3N8 subtype correlates with the replacement of cysteine 50 with phenylalanine and points to this as the site of palmitate attachment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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