Sequence analysis of the glycoprotein 120 coding region of a new human immunodeficiency virus type 1 subtype G strain from Russia
| Autor: | Natalia Karasyova, Vadim Pokrovsky, Selimova Lm, Elena Kazennova, Natalia Ladnaya, Rachanee Cheingsong-Popov, Aleksei Bobkov, Marina Bochkova, Jonathan Weber, Kravchenko Av |
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| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Sequence analysis media_common.quotation_subject Immunology Molecular Sequence Data Human immunodeficiency virus (HIV) HIV Envelope Protein gp120 medicine.disease_cause Peripheral blood mononuclear cell Polymerase Chain Reaction Virus Russia Virology Epidemiology medicine Wife Humans Amino Acid Sequence Phylogeny media_common chemistry.chemical_classification Base Sequence business.industry medicine.disease Infectious Diseases chemistry HIV-1 Glycoprotein business Esophagitis |
| Zdroj: | AIDS research and human retroviruses. 12(14) |
| ISSN: | 0889-2229 |
| Popis: | This paper reports the sequencing of HIV-1 subtype G from the blood sample of a 39-year-old Russian male taken in November 1992. The heterosexual, White male and his wife living in Uzbekistan found in 1991 that they were infected with HIV-1. The man reported living in Mozambique during 1984-85 where he had no sexual relations with African residents, yet was admitted to the hospital on several occasions. However, in 1986-87, shortly after returning to the Soviet Union, he reported having a sexual relationship with a woman other than his wife. That woman and her husband were also found to be HIV-positive in 1991. The subject died in November 1993, and his wife in March 1995. His peripheral blood mononuclear cells were separated and kept at -70 degrees Celsius until used. When the blood sample was obtained, the man had a CD4 count of 10 cells/mcl, had lost more than 10% of his weight, and developed candidal esophagitis and chronic diarrhea associated with Cryptosporidia. |
| Databáze: | OpenAIRE |
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