Thyroid gland in dwarf mice: a stereological study
| Autor: | Stanislaus M. Haumont, Jean-François Denef, André C. Cordier |
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| Rok vydání: | 1976 |
| Předmět: |
Diminution
endocrine system medicine.medical_specialty Histology Biometry endocrine system diseases Thyroid Cell Thyroid Gland Stereology Heterozygote advantage Mice Inbred Strains Cell Biology Biology Growth hormone Molecular medicine Pathology and Forensic Medicine Follicle Mice medicine.anatomical_structure Endocrinology Internal medicine medicine Animals Dwarfism Pituitary |
| Zdroj: | Cell and tissue research. 171(4) |
| ISSN: | 0302-766X |
| Popis: | Stereological methods were used to compare thyroids of dwarf mice and of their heterozygote littermates. In the thyroid of dwarf mice unorganized cellular masses, adipous tissue and ultimobranchial cysts are abundant. Follicles are small and their distribution function is unimodal. The number of cells per follicle is considerably lowered if compared with the normal. In control mice the distribution function of thyroid follicles is bimodal. These data show that origin of the thyroid anomaly in dwarf mice is due to a drastic diminution of cell divisions, probably resulting from the lack of growth hormone. |
| Databáze: | OpenAIRE |
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