Implementation of sentinel node biopsy in breast cancer patients in the Netherlands
Autor: | Jos A.A.M. van Dijck, Petra H.M. Peeters, Ardine M.J. Reedijk, Monique G.G. Hobbelink, Paul J. van Diest, Vivianne C. G. Tjan-Heijnen, Miranda J.M. Dirx, Vincent K Y Ho, Emiel J. Th. Rutgers, Margriet van der Heiden-van der Loo, Michael Schaapveld, Lonneke V. van de Poll-Franse |
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Rok vydání: | 2007 |
Předmět: |
Adult
Cancer Research medicine.medical_specialty Age-related aspects of cancer [ONCOL 2] medicine.medical_treatment Population Sentinel lymph node Breast Neoplasms Molecular epidemiology [NCEBP 1] Negative Axillary Lymph Node Breast cancer Interventional oncology [UMCN 1.5] Breast-conserving surgery Medicine Humans education Mastectomy Aged Netherlands Aged 80 and over education.field_of_study business.industry Sentinel Lymph Node Biopsy Axillary Lymph Node Dissection Sentinel node Middle Aged medicine.disease Surgery Oncology Lymphatic Metastasis Axilla Lymphadenectomy Female Lymph Nodes business |
Zdroj: | European Journal of Cancer, 44, 5, pp. 683-91 European Journal of Cancer, 44, 683-91 |
ISSN: | 0959-8049 1998-2003 |
Popis: | Contains fulltext : 69821.pdf (Publisher’s version ) (Closed access) BACKGROUND: This population-based study describes the implementation of the sentinel node biopsy (SNB) in breast cancer patients in the Netherlands. We examined the extent of use over time of SNB in women who were considered eligible for SNB on the basis of their clinical status. METHODS: The study included a total of 35,465 breast cancer patients who were diagnosed with T1-2 tumours (5.0 cm), negative axillary lymph node status and no distant metastases upon clinical examination between 1st January 1998 and 31st December 2003 in six Comprehensive Cancer Centre regions in the Netherlands. Information on axillary surgery was classified as SNB alone, SNB+axillary lymph node dissection (ALND), ALND alone or none. Patterns of use of axillary surgery were summarised as the proportion of patients receiving each surgery type. RESULTS: Overall, 25.7% of patients underwent SNB alone, 19.1% underwent SNB+ALND, 50.0% had ALND alone and 5.2% did not have axillary surgery. SNB was more common in women who had breast-conserving surgery: 50.5% of patients who received breast-conserving surgery underwent SNB compared to 40.7% of patients who had mastectomy (p |
Databáze: | OpenAIRE |
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