Implementation of sentinel node biopsy in breast cancer patients in the Netherlands

Autor: Jos A.A.M. van Dijck, Petra H.M. Peeters, Ardine M.J. Reedijk, Monique G.G. Hobbelink, Paul J. van Diest, Vivianne C. G. Tjan-Heijnen, Miranda J.M. Dirx, Vincent K Y Ho, Emiel J. Th. Rutgers, Margriet van der Heiden-van der Loo, Michael Schaapveld, Lonneke V. van de Poll-Franse
Rok vydání: 2007
Předmět:
Zdroj: European Journal of Cancer, 44, 5, pp. 683-91
European Journal of Cancer, 44, 683-91
ISSN: 0959-8049
1998-2003
Popis: Contains fulltext : 69821.pdf (Publisher’s version ) (Closed access) BACKGROUND: This population-based study describes the implementation of the sentinel node biopsy (SNB) in breast cancer patients in the Netherlands. We examined the extent of use over time of SNB in women who were considered eligible for SNB on the basis of their clinical status. METHODS: The study included a total of 35,465 breast cancer patients who were diagnosed with T1-2 tumours (5.0 cm), negative axillary lymph node status and no distant metastases upon clinical examination between 1st January 1998 and 31st December 2003 in six Comprehensive Cancer Centre regions in the Netherlands. Information on axillary surgery was classified as SNB alone, SNB+axillary lymph node dissection (ALND), ALND alone or none. Patterns of use of axillary surgery were summarised as the proportion of patients receiving each surgery type. RESULTS: Overall, 25.7% of patients underwent SNB alone, 19.1% underwent SNB+ALND, 50.0% had ALND alone and 5.2% did not have axillary surgery. SNB was more common in women who had breast-conserving surgery: 50.5% of patients who received breast-conserving surgery underwent SNB compared to 40.7% of patients who had mastectomy (p
Databáze: OpenAIRE