Factors affecting treatment adherence to atomoxetine in ADHD: a systematic review
| Autor: | Tamas Treuer, Luis Mendez, William Montgomery, Sheng Hu Wu |
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| Rok vydání: | 2016 |
| Předmět: |
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medicine.medical_specialty business.industry Reason for Treatment Atomoxetine Psychological intervention MEDLINE Review compliance treatment discontinuation 030227 psychiatry Discontinuation 03 medical and health sciences ADHD medication 0302 clinical medicine Tolerability Inclusion and exclusion criteria Medicine adherence business Psychiatry atomoxetine 030217 neurology & neurosurgery Reimbursement medicine.drug |
| Zdroj: | Neuropsychiatric Disease and Treatment |
| ISSN: | 1178-2021 |
| DOI: | 10.2147/ndt.s97724 |
| Popis: | The purpose of this paper was to systematically review the literature related to research about the factors affecting treatment adherence and discontinuation of atomoxetine in pediatric, adolescent, and adult patients with attention-deficit/hyperactivity disorder (ADHD). Medline was systematically searched using the following prespecified terms: “ADHD”, “Adherence”, “Compliance”, “Discontinuation”, and “Atomoxetine”. We identified 31 articles that met all inclusion and exclusion criteria. The findings from this review indicate that persistence and adherence to atomoxetine treatment were generally high. Factors found to influence adherence and nonadherence to atomoxetine treatment in ADHD in this review include age, sex, the definition of response used, length of treatment, initial dose of treatment, comorbid conditions, and reimbursement. Tolerability was cited as an important reason for treatment discontinuation. More research is needed to understand those factors that can help to identify patients at risk for poor adherence and interventions that could improve treatment adherence early in the stage of this illness to secure a better long-term prognosis. |
| Databáze: | OpenAIRE |
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