POPULATION AND MODALITY CHARACTERISTICS OF NEURONS IN THE CORONAL REGION OF SOMATOSENSORY AREA I OF THE CAT
| Autor: | R.W. Morse, R. J. Adkins, A.L. Towe |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Cerebral Cortex
Neurons education.field_of_study Medial cortex Research Population Brain Stimulation Anatomy Biology Somatosensory system Electric Stimulation Electrophysiology medicine.anatomical_structure Developmental Neuroscience Neurology Receptive field Touch Lemniscus medicine Cats Neuron Cuneate nucleus education Neuroscience |
| Zdroj: | Experimental neurology. 11 |
| ISSN: | 0014-4886 |
| Popis: | By extracellular microelectrode techniques, neurons were isolated within the forepaw receiving area of primary somatosensory area I of the cat, just medial to the caudal end of the coronal sulcus. The response properties of 278 neurons were studied from several aspects, including: (a) modality specificity; (b) location and extent of receptive field; (c) responsiveness to direct electrical stimulation of the skin; (d) ability to follow iterative electrical stimulation; and (e) locus of isolation within the cortical tissue. Eighty-two per cent of the neurons responded to touch but not hair stimulation; only 6% were classed as hair sensitive. The receptive fields were uniformly small, the largest identified being 8 cm2, and were located mainly on the distal parts of the forelimb. All these neurons responded to electrical stimulation of the skin, and all tested responded to direct electrical stimulation of the cuneate nucleus. A population analysis revealed that the greatest amount of neuron activity following stimulation of the contralateral forepaw occurred 0.6–0.9 mm below the pial surface, 11–13 msec after the stimulus. The population pattern of response to direct stimulation of the cuneate nucleus was identical to that following contralateral forepaw stimulation—merely shifted 5.2 msec earlier in time. The positive phase of the surface recorded primary evoked response occurred during this peak activity. It is concluded that the afferent input to this region of the cortex comes entirely by way of the dorsal column-medial lemniscus system, for no other afferent influence was found necessary to explain the response pattern. The population response pattern is compared with that from the postcruciate cortex and found to be strikingly different. However, the coronal neuron population displayed an affinity to one particular subset of neurons isolated in more rostral and medial cortex. |
| Databáze: | OpenAIRE |
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