Sarcoidosis is associated with lower risks of penetrating disease and colectomy in hospitalized patients with inflammatory bowel disease
| Autor: | Sushil Ahlawat, Brandon Rodgers, Yi Jiang, Daniel S Rim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Lower risk Inflammatory bowel disease Gastroenterology 03 medical and health sciences 0302 clinical medicine inflammatory bowel disease Internal medicine Medicine penetrating disease sarcoidosis Colectomy Hepatology business.industry Septic shock Odds ratio Original Articles medicine.disease colectomy Ulcerative colitis digestive system diseases Respiratory failure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Original Article Sarcoidosis business |
| Zdroj: | JGH Open: An Open Access Journal of Gastroenterology and Hepatology |
| ISSN: | 2397-9070 |
| Popis: | Background and Aim Inflammatory bowel disease (IBD) and sarcoidosis, primarily considered distinct entities, share commonalties in pathophysiology and clinical manifestations. This study aimed to examine the in‐hospital outcomes of patients with concurrent IBD and sarcoidosis. Methods The National Inpatient Sample was used to identify hospitalized adult patients with IBD and sarcoidosis from 2010 to 2014. Primary outcomes were in‐hospital mortality, rates of septic shock, acute renal failure, respiratory failure, length of stay, and total hospitalization charges. Secondary outcomes were IBD‐specific complications and surgery interventions. Results A total of 3995 patients with IBD and coexisting sarcoidosis (IBD/sarcoidosis), of which 2500 patients had Crohn's disease with coexisting sarcoidosis (Crohn's disease [CD]/sarcoidosis) and 1495 patients had ulcerative colitis with coexisting sarcoidosis (ulcerative colitis [UC]/sarcoidosis), were included. Patients with IBD/sarcoidosis had a lower risk of penetrating disease (adjusted odds ratio [aOR] 0.3, 95% confidence interval [CI] 0.16–0.55, P Sarcoidosis is associated with a lower rate of penetrating disease, leading to less colectomy in patients hospitalized with Crohn's disease and a higher rate of respiratory failure but a lower rate of colectomy in patients hospitalized with ulcerative colitis. |
| Databáze: | OpenAIRE |
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