A case of uveitis due to Rickettsia conorii infection in Southeastern France

Autor: Cecile Caisso, Brigitte Dunais, Dominique Neri, Matteo Vassallo, Jacques Payan
Rok vydání: 2016
Předmět:
Zdroj: Ticks and Tick-borne Diseases. 7:338-341
ISSN: 1877-959X
DOI: 10.1016/j.ttbdis.2015.12.004
Popis: We describe a case of skin rash and bilateral uveitis secondary to Rickettsia conorii infection. A 60-year-old female patient, living in the rural hinterland of Cannes, was referred to our hospital in mid-August 2012 for skin rash, fever, and arthromyalgia. Blood tests showed increased inflammatory markers, hepatic cytolysis and anicteric cholestasis. Ophthalmic examination revealed bilateral papillitis and focal chorio-retinitis. Fluoroscopic angiography demonstrated early hypofluorescence, with a few arteriolar occlusions, and subsequent hyperfluorescence and focal vasculitis. R. conorii antibodies were identified by immunofluorescence antibody test. Investigation of other infective agents and the immunological panel were negative. A 2-week course of doxycycline 200 mg/day was prescribed, and fever rapidly subsided, the skin rash resolved and vision improved. Ophthalmic examination a month and a half later showed almost all retinal lesions had disappeared and inflammation markers had returned to normal.
Databáze: OpenAIRE