Abnormalities of regional distribution of cerebral vasculature in schizophrenia detected by dynamic susceptibility contrast MRI
Autor: | Bruce M. Cohen, Deborah A. Yurgelun-Todd, Perry F. Renshaw, Camper D. English |
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Rok vydání: | 1995 |
Předmět: |
Adult
Male Psychosis Pathology medicine.medical_specialty Hemodynamics Gadolinium Magnetic resonance angiography Basal Ganglia Functional Laterality Cerebral circulation Heterocyclic Compounds Cortex (anatomy) Cerebellum Basal ganglia medicine Organometallic Compounds Humans medicine.diagnostic_test Echo-Planar Imaging Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Psychiatry and Mental health medicine.anatomical_structure Cerebrovascular Circulation Cerebral hemisphere Schizophrenia Blood Vessels Female Occipital Lobe Psychology Magnetic Resonance Angiography |
Zdroj: | The American journal of psychiatry. 152(12) |
ISSN: | 0002-953X |
Popis: | Objective: The authors tested the hypothesis that the regional distribution of cerebral vasculature is anomalous in schizophrenia. Method: Dynamic susceptibility contrast magnetic resonance imaging was used to evaluate cerebral blood volume in the right and left occipital cortex, basal ganglia, and cerebellum of 10 subjects with schizophrenia and I 0 healthy cornparison subjects. Results: Cerebral blood volume was greater in the schizophrenic subjects in every region studied. Conclusions: The findings suggest an abnormality of the configuration of cerebral blood vessels in schizophrenia. (Am J Psychiatry 1995; 152:1801-1 803) |
Databáze: | OpenAIRE |
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