Abnormalities of regional distribution of cerebral vasculature in schizophrenia detected by dynamic susceptibility contrast MRI

Autor: Bruce M. Cohen, Deborah A. Yurgelun-Todd, Perry F. Renshaw, Camper D. English
Rok vydání: 1995
Předmět:
Zdroj: The American journal of psychiatry. 152(12)
ISSN: 0002-953X
Popis: Objective: The authors tested the hypothesis that the regional distribution of cerebral vasculature is anomalous in schizophrenia. Method: Dynamic susceptibility contrast magnetic resonance imaging was used to evaluate cerebral blood volume in the right and left occipital cortex, basal ganglia, and cerebellum of 10 subjects with schizophrenia and I 0 healthy cornparison subjects. Results: Cerebral blood volume was greater in the schizophrenic subjects in every region studied. Conclusions: The findings suggest an abnormality of the configuration of cerebral blood vessels in schizophrenia. (Am J Psychiatry 1995; 152:1801-1 803)
Databáze: OpenAIRE