Meroterpenoids with unknown skeletons from the leaves of Psidium guajava including one anti-inflammatory and anticoagulant compound: psidial F

Autor:	Yue, Yu, Xing-Yan, Sun, Kai-Ling, Xu, Jie, Ma, Ying-Da, Zang, Qi, Hou, Ying, Peng, Chuang-Jun, Li, Dong-Ming, Zhang
Rok vydání:	2022
Předmět:	Plant Leaves Pharmacology Psidium Molecular Structure Plant Extracts Drug Discovery Anti-Inflammatory Agents Anticoagulants General Medicine Skeleton
Zdroj:	Fitoterapia. 159:105198
ISSN:	0367-326X
DOI:	10.1016/j.fitote.2022.105198
Popis:	Four unknown meroterpenoids named as psidials D-G (1-4) together with 5 known compounds (5-9) had been obtained from the leaves of Psidium guajava. Their absolute structures were elucidated by spectral and calculated methods. Psidials DF (1-3) represented unknown carbon skeleton of the 3,5-diformylbenzyl phloroglucinol-coupled sesquiterpenoid. The possible biosynthetic pathway for 1-3 was postulated. In the bioactivity assay, psidial F (3) was found to possess anti-inflammatory and anticoagulant activities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30dfba9a7938c76d3cb422e5f856b59 https://doi.org/10.1016/j.fitote.2022.105198 Zobrazit plný text záznamu Full Text from ScienceDirect