Microbiological, ultrastructural and spectroscopic analyses of the anti-tooth-plaque properties of fluoride compounds in vitro
| Autor: | D.A. Camosci, Norman Tinanoff |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Dental Plaque
Electron microprobe In Vitro Techniques medicine.disease_cause Microbiology Streptococcus mutans chemistry.chemical_compound Fluorides Spectrophotometry medicine Actinomyces Humans General Dentistry Enamel paint medicine.diagnostic_test biology Streptococcus Chemistry Spectrophotometry Atomic Cell Biology General Medicine biology.organism_classification Otorhinolaryngology visual_art Ultrastructure visual_art.visual_art_medium Tin Fluorides Streptococcus sanguis Fluoride Bacteria Nuclear chemistry |
| Zdroj: | Archives of oral biology. 25(8-9) |
| ISSN: | 0003-9969 |
| Popis: | The growth of bacteria on enamel in vitro was used to investigate the effect on plaque formation of 1 min, twice daily exposure to various fluoride treatments. After 2 days, microbial quantitation of the number of adherent Streptococcus mutans, Streptococcus sanguis or Actinomyces viscosus cells showed that in all cases SnF 2 at 100 or 250 parts/10 6 F − significantly reduced the bacteria, whereas NaF (100 parts/10 6 F − ), SnCl 2 (Sn equimolar to SnF 2 at 100 part/10 6 F − ) and Na 2 SnF 6 (100 parts/10 6 F − ) produced no significant change. Electron microscopy of the Strep, mutans specimens exposed to SnF 2 (250 parts/10 6 ) revealed bacterial separation from the enamel and several morphological alterations of the cells themselves. Electron-dense granules, identified as tin by electron microprobe, were also noted in the bacteria exposed to SnF 2 . Atomic-absorption spectrophotometry of similarly processed specimens revealed high levels of tin in plaque samples treated with SnF 2 but not with SnCl 2 . These findings support the view that SnF 2 has anti-plaque properties and that its action may be due to the accumulation of tin in the bacteria. |
| Databáze: | OpenAIRE |
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