Rehydration during exercise prevents the increase of homocysteine concentrations
| Autor: | Marcela González-Gross, Ángel Enrique Díaz-Martínez, Gonzalo Palacios, B. Maroto-Sánchez, Pedro J. Benito, Ciriaco Carru, Domingo González-Lamuño, Jara Valtueña, Angelo Zinellu, Olga López-Torres |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine Homocysteine Medicina Clinical Biochemistry Hyperhomocysteinemia Physiology Creatine Biochemistry Young Adult 03 medical and health sciences chemistry.chemical_compound Folic Acid Isotonic Humans Aerobic exercise Medicine Vitamin B12 Exercise Methylenetetrahydrofolate Reductase (NADPH2) Deportes Creatinine Cross-Over Studies 030102 biochemistry & molecular biology biology business.industry Drinking Water Organic Chemistry Sports drink Vitamin B 12 030104 developmental biology chemistry Methylenetetrahydrofolate reductase biology.protein Fluid Therapy Isotonic Solutions business |
| Zdroj: | Amino Acids, ISSN 0939-4451, 2019-02, Vol. 51, No. 2 Archivo Digital UPM Universidad Politécnica de Madrid |
| ISSN: | 1438-2199 0939-4451 |
| Popis: | This study aimed to assess the effect of rehydration during and after acute aerobic submaximal exercise on total homocysteine (tHcy) concentrations and related parameters in physically active adult males. Twenty trained males (29.4 ± 7.9 years old) completed four exercise tests: two without rehydration during exercise (NH1 and NH2), one with rehydration during exercise using water (H1) and one with rehydration during exercise using an isotonic sports drink (H2). After finishing the exercise tests, subjects followed a rehydration protocol for 2 h. Serum tHcy, vitamin B12, folate, creatine and creatinine were analysed before, after and at 2, 6 and 24 h after exercise. Data were analysed with and without correcting for haemoconcentration to assess the changes in tHcy related. The methylenetetrahydrofolate reductase (MTHFR) 677TT genotype was also analysed. THcy (uncorrected by haemoconcentration) increased significantly after exercise (P |
| Databáze: | OpenAIRE |
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