Isolation and structure elucidation of vancoresmycin - A new antibiotic from Amycolatopsis sp. St 101170
| Autor: | Dominique LeBeller, Cordula Hopmann, Mark Brönstrup, Michael Kurz, Joachim Wink |
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| Předmět: |
biology
medicine.drug_class Stereochemistry Organic Chemistry Antibiotics Tetramic acid Isolation (microbiology) biology.organism_classification Biochemistry Amycolatopsis sp chemistry.chemical_compound chemistry Drug Discovery medicine Fermentation broth Derivatization Derivative (chemistry) Bacteria |
| Zdroj: | Scopus-Elsevier |
| Popis: | A new antibiotic, active against Gram-positive bacteria, has been isolated from the fermentation broth of the actinomycete Amycolatopsis sp. ST 101170. The structure of the compound named vancoresmycin, a tetramic acid derivative with a highly oxygenated long alkyl chain, was elucidated by extensive spectroscopic studies and derivatization. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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