Early and late outcome after elective cardiac surgery in patients with cirrhosis

Autor: Bertrand Nougarede, Jean Luc Michaud, Antoine Ausseur, Philippe Bizouarn, Yann Le Teurnier, Pascal Desseigne, Michel Train
Rok vydání: 1999
Předmět:
Zdroj: The Annals of Thoracic Surgery. 67:1334-1338
ISSN: 0003-4975
DOI: 10.1016/s0003-4975(99)00226-x
Popis: Background . A prospective study was performed to evaluate the early and late outcome after elective cardiac surgery in patients with cirrhosis. Methods . All patients who underwent elective cardiac surgery between 1995 and 1997, and were suspected of having a history of cirrhosis, were followed in the intensive care unit (ICU), during hospitalization and after hospital discharge. All patients received high doses of aprotinin during surgery. Results . Ten patients of Child-Pugh class A and 2 patients of Child-Pugh class B were studied. All patients had signs of portal hypertension, and 11 of 12 patients had thrombocytopenia. In the first 24 h after operation, the median chest tube output was 810 mL (range 350 to 1,500 mL). Median ICU and hospital stays were 3 and 15 days, respectively (range 2 to 10 and 7 to 36 days, respectively). Seven patients experienced postoperative morbidity and 7 patients had significant complications after their hospital discharge. One death occurred in the ICU. Two deaths occurred after hospital discharge and were related to further hepatic damage. Conclusions . These results suggest that, in patients with mild or moderate cirrhosis, the incidence of significant complications was high after elective cardiac surgery, increasing the length of stay in ICU and overall hospitalization time and compromising the health status, even well after the operation.
Databáze: OpenAIRE